This DTxHE report comprises three studies: (a) a systematic literature review, (b) a policy analysis, and (c) a critical analysis on case studies. Both systematic literature review and policy analyses are anchored on the United Kingdom Joint Information Systems Committee’s (JISC) comprehensive framework (2023) for DTxHE. The framework has widely been employed for DT analysis because it provides “a comprehensive perspective on how the digital environment can support positive work, research, and learning experiences, and promote a sense of belonging and wellbeing” (JISC, 2023, p. 6). It consists of six dimensions: (1) organizational digital culture, (2) knowledge creation and innovation, (3) knowledge development, (4) knowledge management and use, (5) knowledge exchange and partnerships, and (6) digital and physical infrastructure.